Gut microbiome data may be helpful in routine screening of cardiovascular disease

Recent studies have found a link between gut microbiota, the microorganisms in human digestive tracts, and CVD, which is the leading cause of mortality worldwide. Gut microbiota is highly variable between individuals, and differences in gut microbial compositions between people with and without CVD have been reported.

“Based on our previous research linking gut microbiota to CVD in animal models, we designed this study to test whether it is possible to screen for CVD in humans using artificial intelligence screening of stool samples,” said Bina Joe, Ph.D., FAHA, the study director, Distinguished University Professor and Chairwoman of the department of physiology and pharmacology at the University of Toledo in Toledo, Ohio. “Gut microbiota has a profound effect on cardiovascular function, and this could be a potential new strategy for evaluation of cardiovascular health.”

Researchers used data from the American Gut Project (an open platform for microbiome research based in the United States) to analyze microbial composition of stool samples with state-of-the-art machine learning modeling. Nearly 1,000 samples were analyzed, and approximately half of the samples were from people with CVD. The model was able to identify different clusters of gut bacteria that could potentially help identify individuals with existing CVD and without CVD.

Among the bacteria identified:

Bacteroides, Subdoligranulum, Clostridium, Megasphaera, Eubacterium, Veillonella, Acidaminococcus and Listeria were more abundant in the CVD group.

Faecalibacterium, Ruminococcus, Proteus, Lachnospira, Brevundimonas, Alistipes and Neisseria were more abundant in the non-CVD group.

“Despite the fact that gut microbiomes are highly variable among individuals, we were surprised by the promising level of accuracy obtained from these preliminary results, which indicate fecal microbiota composition could potentially serve as a convenient diagnostic screening method for CVD,” Joe said. “It is conceivable that one day, maybe without even assessing detailed cardiovascular function, clinicians could analyze the gut microbiome of patients’ stool samples with an artificial machine learning method to screen patients for heart and vascular diseases.”

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Materials provided by American Heart Association. Note: Content may be edited for style and length.

Panelists from last year’s RXA event speak at the A2.AI session about how machine learning & applied AI enable businesses to make informed decisions with data. Tune in to this year’s virtual event.

“Through a series of speaker, panel and networking sessions, RXA and other industry leaders will share how applied AI, predictive analytics, and data visualization are changing how companies tackle complex challenges during these unpredictable times,” said Jason Harper, CEO and founder, RXA.

ANN ARBOR, Mich. (PRWEB)
September 10, 2020

RXA, the international leader in applied artificial intelligence, advanced data science, and analytics allowing companies to make smarter, faster decisions, announced today that it will participate in the second annual A2.AI conference – this time, virtually.

The virtual conference is the first of its kind in the Ann Arbor area, focusing on how machine learning and applied artificial intelligence enable businesses to make more informed and actionable decisions with their data. The conference will host leaders and entrepreneurs from companies including RXA, Weave Workforce and ESPN and will ignite new conversations in the artificial intelligence space.

“Many businesses have not begun to utilize the power of applied AI, viewing it as something to tackle in the future. Through a series of speaker, panel and networking sessions, RXA and other industry leaders will share how applied AI, predictive analytics, and data visualization are changing how companies can tackle complex challenges during these unpredictable times,” said Jason Harper, chief executive officer and founder, RXA. “The exponentially rising influx of customer data has impacted every industry around the globe in various ways, and we have the ability using advanced technologies to better plan for the future of business if we can learn from and share best practices from other industry executives.”

The conference will be held on September 23, 2020 from 12:00 p.m. – 4:30 p.m. EDT. Roundtable speakers at the virtual event will include: Mike McFall, CEO and co-founder, BIGGBY COFFEE; LTG Reynold Hoover, retired LTG and principal, RNHoover Consulting LLC.; Doug Kramon, senior director of Fan Support & Customer Care Operations, ESPN; Charles Cantu, founder and CEO, RESET DIGITAL; Amy Klinke, senior director, Business Engagement Center, University of Michigan; Kristie Rowley, principal data scientist, manager of Data Science Professional Services, Domo and; Jason Harper, CEO and co-founder, RXA.

RXA featured speakers will include John Larson, co-founder and CEO of Weave Workforce https://www.weaveworkforce.com/ Jonathan Prantner, cofounder and chief analytics officer, RXA, Eric Green, chief executive officer, Ready Signal https://www.readysignal.com/ Heather Reed, chief experience officer, RXA and Tom Stanek, president RXA https://RXA.IO

For more information about the A2.AI event, please visit https://a2.ai

If you are interested in attending, please register here https://a2.ai/homepage/register/

RXA

RXA https://RXA.IO is a leading applied artificial intelligence and data science company founded in 2016 in Ann Arbor, MI. RXA has a diverse portfolio of services and solutions such as being a leading DOMO implementation and consulting firm, customized artificial intelligence kick-start programs, and an RXA Studio to support the development of new products and companies and proprietary solutions such as Mixed Media Optimization, Voice of Customer, and Workforce Optimization to help organizations improved their ROI and decision making while streamline operations.

RXA’s solutions are currently being leveraged by over 70 different customers across North America, Asia, and Europe. RXA has been named the 2019 Innovative Partner of the Year, Voice of Customer Experience | Application of the Year for 2020, and 2020 Rising Star by Domo, Inc.

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